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When performed by a trained therapist, MLD is gentle and safe even during early postpartum recovery
Both differentiation and osteolytic activity of osteoclasts requires macrophage colony-stimulating factor (M-CSF) and membrane-bound receptor activator of NFB ligand (RANK-L), which are both produced by osteoblasts and by stromal cells
This can result in tissue and cellular damage, DNA strand breaks, and apoptotic cell death
