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Second, variations in EVs composition can serve as biomarkers, and the levels of their surface proteins or miRNAs are strongly linked to the prognosis for sepsis, coagulation abnormalities, or the severity of pneumonia

(2018) 173:17281741.e13

The stability of enzymes is heavily influenced by the solvent environment
Therefore, while existing evidence supports low local toxicity, comprehensive in vitro and in vivo immunogenicity testing remains advisable prior to clinical translation [71, 191]
