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Error 6: Using an imprecise syringe The problem: Large syringes with poor markings lead to imprecise doses (e.g., 0.2 ml plus or minus 0.05 ml error)

Finally, epigenetic regulation via histone modification, such as acetylation of methylation at the NLRP3 promoter and DNA methylation, silences NLRP3 expression and further refines its transcriptional control, highlighting the intricate regulation of this critical inflammasome component [52]

doi: 10.3389/fphar.2026.1780815 Received 04 January 2026 Revised 30 March 2026 Accepted 30 April 2026 Published 05 June 2026 Volume 17 - 2026 Edited by Galina Sudina, Lomonosov Moscow State University, Russia Reviewed by Shangkun Ou, Affiliated Hospital of Guizhou Medical University, China Hyeongjwa Choi, Chungnam National University Hospital, Republic of Korea Updates Copyright 2026 Gallo Afflitto, Fanelli, Petrone, Chirico, Ceccarelli, Martucci, Minutolo, Aiello, Garaci, Matteucci and Nucci

Sahl for reading the manuscript and making comments, A