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It has been found that estradiol benzoate, for example, causes a change in the expression of ECS components (CB 1 R, CB 2 R, FAAH) in the rat uterus, in an estrogen receptor-dependent way, indicating potential for hormonal regulation of the ECS in reproductive tissues (Maia et al., 2017)

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rebaudiana metabolites can activate sweet taste receptors (T1R2/T1R3) in the intestine, promoting glucose absorption and insulin secretion (Meyer-Gerspach et al., 2016)

have found that elevated IOP may trigger a series of parallel and interacting pathological processes, including direct axonal damage, weight-bearing tissue failure, and disruption of the microvascular supply (68)