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Description
Tambin suele asociarse con la obesidad y puede causar sntomas debido a unos niveles elevados de hormonas masculinas (andrgenos)

Alternatively, preclinical studies using leptin-deficient animals ( ob/ob mice) demonstrated that restoring plasma leptin concentration to normal improved heart function after MI, and that these beneficial effects were associated with reductions in cardiac inflammation and apoptosis [13, 14] and activation of anti-hypertrophic pathways in obese animals with left ventricle (LV) hypertrophy [8]

Furthermore, it has an increasingly important role in the diagnosis of familial dysbetalipoproteinaemia (FDBL or Type III), which has lipid parameters that may overlap with other lipid disorders, making diagnosis from a standard profile sometimes difficult

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