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Conversely, prior studies based on reporter gene assays showed that high concentrations of DEHP, DBP, and DnBP exerted TR antagonistic activities [124,125]
While this should logically increase the muscle-building effects, IGF-1 LR3 would also then bypass the internal feedback regulatory pathways, theoretically increasing the risk of negative side effects of excessive growth hormone pathway activity
PLoS ONE 18 , e0281954 (2023)
beta cell function and insulin resistance in lean cases with polycystic ovary syndrome
