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Their significance in the mechanism of breast cancer tumorigenesis is highlighted by their proposal as potential biomarkers of its prognosis (discussed in Section 5)

Aberrant lipid metabolism promotes prostate cancer: Role in cell survival under hypoxia and extracellular vesicles biogenesis

Research shows it stimulates fibroblast proliferation, supports collagen synthesis, promotes angiogenesis via VEGF pathways, modulates matrix metalloproteinase activity, and upregulates key growth factors involved in connective tissue repair

JHU395 can prolong the median survival of mice bearing human MYC-amplified medulloblastoma xenografts from 26 to 45 days (Pham et al., 2021)