mercury glutathione synthesis Methylmercury alters homeostasis by inhibiting glutaredoxin 1 and enhancing glutathione biosynthesis in cultured human astrocytoma cells Glutathione-related genetic polymorphisms are associated
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Wei Z., Ye S., Feng H., et al., Silybin Suppresses Ovarian Cancer Cell Proliferation by Inhibiting Isocitrate Dehydrogenase 1 Activity, Cancer Science 113, no

Cancer invasion and the microenvironment: plasticity and reciprocity

Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion

However, this feature of astrocytes to modify and thereby inactivate xenobiotics has also to be considered in the context of the application of therapeutic drugs for the treatment of neurological disorders, as GSHdependent removal of such compounds in astrocytes may lower the therapeutic benefit of a given treatment
