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Description
MUC1-C chronically activates IFN- through the JAK1/STAT1/IRF1 pathway and induces IDO1 and cyclooxygenase2 (COX2)/PTGS2 effectors, which play an important role in immunosuppression
Professional consensus emphasizes that short-term use is key, with most specialists suggesting a maximum of 3-6 months before taking a break to prevent potential side effects
A clinical study reported that the very low-calorie ketogenic diet (VLCKD) improved ovarian function in obese women with PCOS
10.1016/j.esmoop.2021.100064 48 HahY
