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Dan Barouch, director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, said recent lab studies have shown people who had been infected by an XBB omicron subvariant within the last six months generated antibodies against EG.5, BA.2.86 and other omicron subvariants, suggesting the updated booster will also provide protection against these strains

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116,126 Specifically, CCS-overexpressing SOD G93A mice exhibit significantly decreased COX activity when these mice reached the end stage of disease, whereas SOD G93A mice not overexpressing CCS had no apparent decrease in COX activity at the same stage, 126 supporting the hypothesis that overexpressing CCS increases the delivery of Cu to SOD1 while reducing the delivery of Cu to other enzymes (e.g., mitochondrial cytochrome c oxidase), thus leading to additional toxic effects

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