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doi: 10.3233/JPD-225068 152

A number of factors such as age, hormones, genetic distribution climate, pollution, chemical exposure etc

Genomics 9 , 2942 (2008)

A review of forty-nine observational studies published in the May 2011 issue of the Cochrane Database of Systematic Reviews concluded that higher selenium exposure reduces overall cancer incidence by about 34 percent in men and 10 percent in women, but notes these studies had several limitations, including data quality, bias, and large differences among different studies
