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Immunodetection was carried out using an enhanced chemiluminescence (ECL) detection reagent (Amersham Biosciences, Uppsala, Sweden)

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Harmful Effects of Energy Drinks on the Cardiovascular System In summary, although it is difficult to unambiguously assess the cause-and-effect relationship between ED use and observed adverse health effects without question, the most documented AEs associated with EDs are those affecting the cardiovascular system