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Learning from these species, preservation of living organisms in a supercooled state can enable deeper metabolic stasis compared to hypothermic storage and prolong preservation times

doi: 10.1016/S0098-2997(97)00008-3

Dysfunction of vascular endothelial cells is an initial contributor to cardiovascular disease (Strain and Paldnius, 2018)

This phenomenon is reminiscent of autoprotection observed in experimental animals, where initial exposure to the sub-toxic doses of acetaminophen protects rodents from subsequent lethal doses of the drug [59,60]
