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Description
As peptide bonds break down, byproducts can form that trigger immune responses or localized injection-site reactions
PMID: 11524632
Evaluation of N-glycosylation of secreted proteins N-glycosylation was evaluated by comparative WBs under basal conditions and after digestion with neuraminidase ((2 3, 6, 8, 9)) from Arthrobacter ureafaciens , Sigma-Aldrich), following the manufacturers instructions, and with N-glycosylase F (PNGase F, Sigma-Aldrich, Madrid, Spain)
Think of the peptide as a key and the receptor as a lock: constant use wears the mechanism, and a planned off period lets it resensitize
