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Under arsenite stress, this METTL3/YTHDF2 interaction is inhibited, which stabilizes CHAC1 mRNA and increases its expression ( In addition to arsenite-induced expression, the CHAC1 gene is transcriptionally activated during cysteine, serine or arginine depletion (Ward et al., 2024)

Elevate your head with an extra pillow, avoid eating within 3 hours of bedtime (postprandial vagal activation compounds the effect), and check your magnesium status with a serum or RBC magnesium test

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