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However, their clinical use is restricted by safety concerns and suboptimal pharmacokinetics
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The entire sample was then subjected to ultrasonication in an ice-water bath for 30 min and subsequently cooled in a refrigerator at 20C for 20 min
The decline of dopaminergic neurons due to ROS is linked to reduced glutathione levels and elevated levels of metals such as iron and calcium in the substantia nigra pars compacta [39]
