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Description
LPL is involved in the uptake of fatty acids into adipose tissue by mediating the hydrolysis of triacylglycerol (TAG) laden lipoproteins into free fatty acids (FFAs) (thin arrow)
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Collectively, our study unveils a novel mechanism whereby MFAP2, secreted by CAFs, activates the ITGB8FAKERK1/2ETS2CYP27A1LXR signaling pathway, leading to the suppression of CD8 + T cell function and promoting malignant tumor progression in CRC
The P in GLP-1 stands for peptide
