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Therefore, influx of glutathione from the cytosol into the ER was suggested to increase following proteasome inhibition

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In synthesis, while THC has exhibited promising pharmacological activity, the existing body of research confronts challenges related to its limited bioavailability, the uncertainty of its long-term toxicity, and the pronounced individual differences in its response

Recently, innovative nasal drug delivery systems have been developed to maximize its bioavailability by enhancing the solubility, permeability, and retention time at the nasal mucosa