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[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Kaneko K., Sawada S., Satake C., Kondo K., Izumi T., Tanaka M., Imai J., Yamada T., Katsushima H., Fujishima F., Katagiri H

Funding Statement Deans Award, Pritzker School of Medicine, The University of Chicago

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In the case of NE, interaction in the binding site results in the displacement of water with no consequent conformational changes, therefore resembling a lock-and-key association
