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Characteristic alterations in gut microbial composition in DKD include a marked reduction in short-chain fatty acid (SCFA)-producing bacteriaparticularly butyrate-producing members of the Lachnospiraceae family and genera such as Blautia and Faecalibacteriumalongside an overgrowth of potentially pathogenic taxa, including Enterobacteriaceae and other gamma-proteobacteria (86)

examples of suitable fluorescent materials include umbelliferone, fluorescein, fluorescein isothiocyanate, rhodamine, dichlorotriazinylamine fluorescein, dansyl chloride or phycoerythrin