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Pitfalls of antioxidant supplementation therapy While the cellular localization of endogenous antioxidants (enzymes) is largely known, substantially less information is available about the cellular and tissue localization of low-molecular-weight antioxidants, such as vitamins C and E, carotenoids, flavonoids, and other antioxidants

Targeting RAGE signaling in inflammatory Disease[J]

The complex interaction relationship between iron metabolism disorders and changes in the abundance of gut microbiota (especially Bifidobacterium ) revealed in this section provides evidence for clarifying the molecular mechanism of the hypothetical pathological axis of iron overload-disruption of gut homeostasis-ferroptosis in OA, and suggests that targeted regulation of the iron-microbiota interaction may become a potential new strategy for the prevention and treatment of OA

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