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The discovery of robust predictors of treatment response could enable the prediction, from the outset, of a persons probable treatment journey, and thereby pave the way for precision medicine through the clinical implementation of combined phenotypic and genotypic prediction models

In recreational athletes, supraphysiological GH doses are often used either alone or in combination with other doping substances (140), and studies have shown that GH improves anaerobic sprint capacity, but not strength and endurance (141), and increases GH, IGF-I and fasting insulin levels (142, 143) mimicking those seen in acromegaly patients ( Table 1 )

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[DOI] [PMC free article] [PubMed] [Google Scholar] 107.de la Cruz-Lpez KG, Castro-Muoz LJ, Reyes-Hernndez DO, Garca-Carranc A, Manzo-Merino J