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How do cells cope with RNA damage and its consequences
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IGF-1 binds IGF-1R with 10 times greater affinity than IR
This indicates that survival is critically dependent upon GSH, and therefore is not being sustained by an alternative Trx-disulfide reductase, such as by repurposing of either the mitochondrial TrxR2 or the testis-specific Tgr (TrxR3) [48, 109]
