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There is no significant association between B12 levels and any blood parameters (eg macrocytosis), neurological symptoms or psychological symptoms (as measured by K10)

Most of the data, I will say, are from looking at people who first received the AstraZeneca vaccinewhich is made from the same technology that created the J&J vaccinethat really does show important boosting of the protective effect with an mRNA vaccine given as a second dose

The reason is that B12 absorption is a complex process with multiple steps involved and which decline with age

Enhanced Bioavailability: Natural forms of Vitamin B12 are often better absorbed and utilized by the body, leading to more efficient delivery of its crucial benefits