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Taken together, the activation of oxidative and inflammatory pathways in cerebral endothelial cells provides a crucial route for translating peripheral inflammatory and oxidative stress signals through the BBB into the brain parenchyma
The role of IGF in cancer risk is multifactorial and taken together, the preponderance of data suggests a slight increased risk of some cancers due to higher activity of the IGF system
W., Olson, M., Purpura, M., and Jager, R
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