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Mathematical modeling of liver injury and dysfunction after acetaminophen overdose: Early discrimination between survival and death

10.1161/01.CIR.0000109496.82683.49 Circulation 165 ShimamuraM.SatoN.WaguriS.UchiyamaY.HayashiT.IidaH.et al (2006)

Available evidence, primarily from case reports and post-marketing surveillance, suggests that gastrointestinal symptoms related to GLP-1 receptor agonists are typically reversible upon discontinuation of the medication, though the timeframe and extent of recovery can vary considerably between individuals

With the development of nanotechnology, the biomaterials-based nanoagents may achieve passive (e.g., ELVIS and Bionic effect, pH, ROS and enzyme-dependent) or active (specific ligand or non-serum based biomarkers dependent) targeting and other functional effects (e.g., multi-enzyme activities, anti-inflammation and anti-oxidation effect) for AP treatment