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Again, in the first study using FOXO4-DRI to induce apoptosis in senescent cells, the senescent cells were generated by irradiation or doxorubicin ( As shown in Figure 3, FOXO4-DRI pre-treatment is the dedifferentiation of chondrocytes during the in vitro expansion

As we age, everyday wear and tear causes our tendons to slowly weaken

With further research, it is expected to transform from a research tool into a clinical drug, filling the niche in targeted metabolic therapy, especially in the combined intervention of obesity and type 2 diabetes, where it holds unique application potential

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