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Description
Mice that received choline intraperitoneally before and during sepsis exhibit lower levels of plasma blood urea nitrogen (BUN) and creatinine, as well as urine neutrophil gelatinase-associated lipocalin (NGAL) levels compared to septic mice treated with vehicle
The studies above focused on skeletal muscle, but this dysregulation in carnitine metabolism may be found in other tissues and cause other ZDV-induced ADRs such as hepatic lipid accumulation (hepatic steatosis)
8A) manner, at concentrations (10100 M) relevant to human disease (up to 150 M in patients with CKD) 19
Fleshner, Stephen B
