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Apart from neutralizing free radicals, N-acetylcysteine also regulates the Foxo3a/TRIM69/p53 pathway attenuating Foxo3a phosphorylation and TRIM69 expression with a subsequent reduction in p53-induced apoptosis [62]

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Ultrasound imaging and BBB opening experiments validated the ability of LIFU-mediated Curcumin-PLGA nanoparticles to effectively deliver curcumin into deep brain regions

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Song, H., Lopes, K., Orr, A

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