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This interplay has also been proposed in gliomas, as monocarboxylate transporters (MCTs), specifically MCT1 and MCT4, are highly expressed in brain tumors and mediate proton-coupled transport of L-lactate, ketone bodies, and pyruvate (81)

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In the long term, overcoming these limitations requires: (1) developing standardsfor example, establishing recommended hydrogen levels in water, measurement methods, and shelf-life guarantees for H 2 content