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Curr Opin Lipidol 18(4):401408 Hovingh GK, Gandra SR, McKendrick J, Dent R, Wieffer H, Catapano AL, Oh P, Rosenson RS, Stroes ES (2016) Identification and management of patients with statin-associated symptoms in clinical practice: a clinician survey

EG was responsible for data collection, input and analysis as well as manuscript preparation

This is coupled with an exaggerated inflammatory response driven by the intestinal microbiota, leading to extensive infiltration of various immune cells, including T cells, B cells, dendritic cells (DCs), macrophages, and neutrophils, into the lamina propria

Systemic Inflammation: By preventing the accumulation of toxic lipid intermediates in the cellular cytoplasm, L-carnitine reduces the generation of reactive oxygen species (ROS), helping to lower systemic inflammatory markers like C-reactive protein (CRP) and stabilize mast cell reactivity