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The Y951 residue is more specific, causing Src activation and VE-cadherin phosphorylation

doi: 10.1136/bmj.h1603 Piechota, M., Krl, R., Elias, D., Wawrzynek, W., & Lekstan, A

There is also a very safe profile (lethal dose (LD1) could be not achieved) [84], a point recently confirmed in a large study conducted by Xu and collaborators [85]

Natural bioactive compounds derived from plants have also demonstrated benefits in preclinical and clinical studies for ASD management [132]
