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10.1038/srep27915 90 RoloA
4073, 1973, pp
Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action
To maintain systemic copper homeostasis within physiological limits, cells employ a complex regulatory network of copper enzymes, molecular chaperones, and membrane transport proteins, which collaboratively regulate copper uptake, efflux, and utilization ( The absorption of dietary copper predominantly occurs in the small intestine and duodenum, primarily mediated by the copper transport protein 1 (CTR1), also known as solute carrier family 31 member 1 (SLC31A1), located on the apical side of intestinal epithelial cells (125)
