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Mineroff J, Nguyen JK, Jagdeo J
Using the calculated kinetic parameters for GSH export from control and ritonavir-treated astrocytes to calculate the GSH export velocity for the cytosolic concentration of 8 mM GSH, we obtained initial export rates of 3.3 nmol/(mg x h) (control) and 10.9 nmol/(mg x h) (ritonavir)
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While adaptive in metabolically healthy individuals, these hormonal changes may require clinical attention in patients with pre-existing thyroid disorders or stress-related endocrine dysregulation
