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We show that gp34 1-179 binding to membrane (m)IgG results in activation of the PDK1/AKT/mTOR/S6 pathway and BCR internalization, in a SYK-independent manner, and subsequently induces expression of early activation markers

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6 Conclusion We have manually constructed miRNAproteinmetabolite interaction networks such as hsa-mir-122-5pIL6bilirubin, hsa-mir-122-5pGSTM2 - butyric acid (butyrate), hsa-mir-30c-5pGPX3 - butyric acid (butyrate), hsa-mir-30d-5pGPX3butyric acid (butyrate), and hsa-mir-22-3pACADMoctanoylcarnitine (octanoylcarnit.)

Kocher-Debre-Semelaigne syndrome: hypothyroid muscular pseudohypertrophy a rare report of two cases