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It is thought that bioactive peptides derived from whey proteins as a result of gastrointestinal digestion or bioactive peptides in the whey protein mixture with antioxidant properties may also play a role in improving liver and kidney damage caused by MTX

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However, several challenges remain, including the black box nature of AI systems (such as issues of model interpretability and liability in AI-assisted diagnosis), reliance on high-quality annotated data, limited generalizability across real-world clinical settings (including model performance stability across novel scenarios, devices, diverse populations, and disease stages), and the potential for algorithmic bias (leading to diagnostic disparities due to overrepresentation of certain demographic groups in training data)

103 Moreover, altered cytokine production, impaired phagocytosis, and reduced lymphocyte proliferation are among the functional changes observed