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So, for example, 8M urea or 6M guanidine HCl would likely denature GST, preventing the GST-glutathione interaction that serves as the foundation for this purification

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Byungheon Lee at Kyungpook National University in Daegu, South Korea, and co-workers reviewed progress into novel therapeutic systems that use tumour-homing peptides to target solid tumours

These modifications stabilize the molecular structure, allowing it to mimic the amphipathic alpha-helix of the native hormone