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Description
96,97 TGF- also induces and promotes the increased expression of EGF, EGFR and its related signalling pathways, and their synergism induces EMT-related phenotypic changes
Mitochondria are central to ROS production and cell death (Lo et al., 2003)
Both reduction and mutation in TDP-43 or SOD1 have been reported in mice to disrupt Gem assembly or stabilization 29,30,31,32
There is a crucial direction for future research to include such a group, with the necessary ethical approvals, to further elucidate the interplay between diabetes, CVD, and the investigated biomarkers
