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most evidence is preclinical and observational
Notably, these nutrient differences appear to have functional significance: correlations between lower vitamin D/higher homocysteine, and greater symptom severity (e.g., higher Childhood Autism Rating Scale scores) were reported, suggesting these biomarkers may influence or reflect the pathophysiology of ASD, not just correlate with its presence [9]
Animal models exposed to 5-Amino-1MQ demonstrate accelerated lipid metabolism and extensive white adipose tissue remodelling, driven by up-regulated SIRT1 activity
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