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To address this critical gap, we utilized the Neuroligin 3 R451C knockin (NL3 R451C KI) mousea well-characterized genetic model of ASD that robustly recapitulates hallmark behavioral features, including social impairments, stereotyped behaviors, and cognitive inflexibility [17, 18]

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It's fine to apply it to the entire face, or you can target blemished areas as needed