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Think about it: when you take an oral supplement, it must journey through your entire digestive system before reaching your bloodstream

10.1016/j.neuroscience.2013.06.059 Neuroscience 161 SeibtJ.DumoulinM

therefore, it is advised that patients older than 50 years and vegans or strict vegetarians should consume foods fortified with vitamin B12 or take vitamin B12 supplements to avoid vitamin B12 deficiency

Sensitivity analysis The results were insensitive to variations in the identification of cohort 2 (Table 5)