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Targeting this signaling pathwayby inhibiting C/EBP or miR-335-5p, or activating PRKAA2/AMPKmay provide a promising therapeutic strategy for MASLD.

Chemically, glutathione is a simple molecule composed of three protein building blocks or amino acids- cysteine, glutamine and glycine. While certain vitamins, minerals and phytochemicals also act as antioxidants, glutathione is different because it is intracellular and produced inherently within a well-nourished and healthy body