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It inhibits tyrosinase, a key enzyme involved in melanin production, and it also shifts melanin synthesis towards lighter pheomelanin rather than darker eumelanin, contributing to brighter-looking skin. Mechanism of action on pigmentation Melanin is the pigment responsible for skin colour, and its overproduction contributes to tanning, dark spots, and uneven tone
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This section highlights how the dynamic regulation of the autophagy machinery underlies astrocytic adaptability in response to pathological stressors such as A accumulation
In Section 3.4, we study the difference in response to acetaminophen (APAP) overdose in males and females after an overdose
