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While the emphysema state results in loss of alveolar spaces and low sputum production, the bronchitis phenotype results in narrowing of the airways as well as blocking of the alveolar spaces with mucus obstruction leading to chronic cough, sputum production, and exacerbations (Szalontai et al., 2021

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Since sleep problems are a common comorbidity associated with ADHD, and because disturbed sleep may be linked etiologically to this disorder, L-theanine may represent a safe and important adjunctive therapy in childhood ADHD

the long-term human safety profile remains unknown