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Description
When an individual has an MTHFR polymorphism, their body struggles to efficiently convert synthetic cyanocobalamin (the cheap form of B12 found in most standard supplements and fortified foods) into the active methylcobalamin required by the cells

Evidence for oxidative pathways in the pathogenesis of PD: are antioxidants candidate drugs to ameliorate disease progression

A., Naser A

Diet, sleep, hydration, and sun protection all play a role