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1 2 "SIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation"
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The above calculation is obviously simplistic as the rates of the two reactions will vary as a function of changes in substrate concentrations following the onset of stress, and kinetic modeling would be required to examine the question more closely
Calabrese plays a central role in the collaborative network, serving as the most critical contributor to the hormesis study
