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LOV (light, oxygen, or voltage) domains of the blue-light photoreceptor phototropin (nph1): binding sites for the chromophore flavin mononucleotide

The conflicting results highlight the complexity of ALAs action and suggest that its efficacy may vary depending on factors such as dosage, duration of treatment, and patient population

According to few recent studies, treatments with hemin can attenuate cytokine storms in animal model of sepsis, indicating the putative role of HO-1 in the protection against the cytokine storm syndrome observed in COVID-19 patients (244)

combining anti-inflammatory and antioxidative therapy with mitochondrial-targeted treatment may enhance overall treatment safety and efficacy