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MTHFR mutations are linked to issues with heart health, neurotransmitter production, detoxification, pregnancy loss, neural tube defects, and behavioral disorders
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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Akinyemi F.T., Adewole D.I
151 For the NADPH-synthesis enzymes involved in anapleurotic reactions, including IDH1/2, ME1/2/3, and CPT1/2, the targeting inhibitors are also being extensively developed
