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In view of the protection of VB 12 in CBS deficiency disease [2], we exogenously administered VB 12 into mice to evaluate whether it is beneficial to AP
Pretreatment with Gem, but not nutlin-3, also delayed the onset of ferroptosis in p53 null H1299 cell lines (Fig S3A and B)
BRCA1 down-regulates cellular levels of reactive oxygen species
In this regard, the fact that during the process of oxidative phosphorylation, electrons leak and subsequently interact with molecular oxygen to form superoxide or other ROS may be relevant 44,45,46
