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Mentale und krperliche Leistungsfhigkeit - auch hier sind die Mitochondrien gefragt

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Molecules 2014;19:211270-21153

TMAO can upregulate scavenger receptors, such as cluster of differentiation 36 (CD36) and scavenger receptor class A type 1 (SR-A1), and promote the formation of foam cells, leading to development and progression of atherosclerosis ( Atherosclerosis: TMAO Activates ERS The ER, formed in continuity with the outer membrane of the nuclear envelope, plays a key role as a central eukaryotic membranous organelle and is responsible for the synthesis, folding, and maturation of membrane and secreted proteins, lipid biosynthesis, and calcium storage ( via ERmitochondrial stress in vitro and aggravates aortic valve lesions in mice ( Thrombus Formation: TMAO Promotes Platelet Reactivity Normal platelet function is essential for hemostasis and maintenance of a closed circulatory system